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Additionally, individuals with this dopamine D2 receptor gene polymorphism were shown to have a deficit in learning from errors in a feedback-based learning task. The sex act is the final common pathway for reproduction. Differences in the motivational potency of food cues and the reactivity of the reward system were also found in obese individuals. In summary, feelings of romantic love use reward and motivation systems consistently, across individuals and across circumstances of the love experience.

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In healthy adults, a negative correlation was found between BMI and baseline brain glucose metabolism in both prefrontal areas and in the anterior cingulate gyrus [ ], and both of these areas notably have been suggested to be directly involved in drug addiction. For example, a study of regional brain metabolism at rest revealed differences between lean and obese individuals.

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Alternatively, given the generality of the decrements of dopamine D2 receptors, it has been posited that reductions in the dopamine system may be a marker for vulnerability or predisposition to excessive or addictive behaviors [ 11 ]. Frascella, rapidly-advancing brain and genetic data may indeed help us move beyond BMI, enabling us to identify obese individuals who have brain differences e. If they are based on survival systems, then the underlying physiological systems must be complex and redundant, exist at many levels of the brain, and be especially difficult to moderate.

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Overlapping mechanisms and functional processes underlying both obesity and addiction are being elucidated in a growing number of human brain imaging studies. This finding of decreased cognitive function in obesity is consistent with a growing literature showing that elevated BMI is associated not only with adverse health outcomes, but also adverse neurocognitive and neuropsychological outcomes in adults e. In moderation, these behaviors are necessary. In contrast to prior revisions, DSM V is considering whether addictions can be defined apart from drug-taking a fundamental shift in the way these disorders have previously been viewed.

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However, a speculation is justified that associates survival-level natural rewards with substance addictions, expanding the brain systems to be addressed in therapy, and increasing our understanding of the necessary tenacity of the behaviors. We found in a brain mapping study that early-stage romantic love activates the VTA of the midbrain and the caudate nucleus, suggesting that it does, indeed, use brain systems that mediate mammalian reward and drives, and is not so much an emotion as a survival motivation [ ]. Having previously established that striatal dopamine D2 receptors levels are lower in obese individuals, Volkow et al.

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